The regenerative family
Polynucleotides, platelet preparations, growth factors, conditioned media, skin boosters and biostimulators, treated as one family with different logic.
What regenerative actually means as a scientific claim
Regeneration, repair and remodelling are different biological outcomes. Most aesthetic treatments described as regenerative produce the second or third.
Polynucleotides: what the molecule is
What polynucleotide injectables are made of, the proposed mechanisms, and how the evidence for them compares with the confidence of the marketing.
PRP and PRF: what actually differs
Platelet rich plasma and platelet rich fibrin, how preparation changes composition, and why heterogeneous protocols make the literature hard to pool.
Growth factors in topical and injectable products
What growth factors are, why size and stability limit topical delivery, and what a growth factor claim on a label does and does not establish.
Skin boosters and what they are not
What a skin booster does physically, why hydration is a real but distinct effect, and where the category gets conflated with signalling treatments.
Biostimulatory injectables and the response they provoke
Poly-L-lactic acid and calcium hydroxylapatite work by provoking a controlled tissue response to a foreign material. What that means for results and for risk.
Microneedling as a delivery route, and as a confounder
Why microneedling is paired with topical preparations, what it does on its own, and why that makes attribution of results unusually difficult.
Stem cells versus cell-free products
What a stem cell product is, what cell-free means, and why the difference matters both biologically and for how a product is regulated.
The rise of regenerative aesthetics in London, and what the practice actually looks like
A London scene report on where regenerative aesthetics is practised, how the category took hold in the capital, and what the science does and does not support.
The science briefing
One email a fortnight. What was published in extracellular vesicle and regenerative aesthetics research, what it actually showed, and which claims moved on our grading scale. Written for people who read the methods section.
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